ENKUR

Across TCGA cell cohorts, ENKUR RNA expression is significantly associated with the go_rna of many other GO terms, with 2,405 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ENKUR-associated GO terms across cancer lineages are Regulation of RNA splicing, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Positive regulation of viral process. Each is linked with ENKUR in more than 8 cancer types. Because this analysis shows association rather than direction, both ENKUR-to-partner and partner-to-ENKUR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of RNA splicing grouped by ENKUR-low versus ENKUR-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENKUR→partner) and Y-score (partner→ENKUR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of RNA splicing →	+0.069	+0.435	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.034	+0.372	.005	.003	3	9
LARGE_INTESTINE	Positive regulation of viral process →	+0.069	+0.229	<.001	<.001	3	7
BLOOD_Lymphoma	Positive regulation of intracellular protein transport →	+0.034	+0.504	.001	.002	3	7
LUNG_NSCLC_LUAD	Sodium ion transmembrane transport →	-0.057	-0.500	<.001	.001	3	7
LUNG_NSCLC_LUSC	Establishment of Golgi localization →	+0.167	+0.295	<.001	.004	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,405 associations by consensus.

Regulation of RNA splicing by ENKUR expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →