ENKUR

mutation — cross-omics
Cross-omicsMUTATION → DRUGCell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ENKUR mutation is significantly associated with the drug of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ENKUR-associated genes across cancer lineages are CZC24832, Fulvestrant, and CCT007093. Each is linked with ENKUR in more than 1 cancer types. Because this analysis shows association rather than direction, both ENKUR-to-partner and partner-to-ENKUR results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CZC24832 grouped by ENKUR-low versus ENKUR-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENKUR→partner) and Y-score (partner→ENKUR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINECZC24832 →+0.290+2.646.025.04731
LARGE_INTESTINEFulvestrant →+0.332+2.649.045.04621
LARGE_INTESTINECCT007093 →+0.322+2.649.030.04611
LARGE_INTESTINEWnt-C59 →+0.427+2.646.014.04711
LARGE_INTESTINE50869 →+0.523+2.649.012.04611
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

CZC24832 by ENKUR expression — LARGE_INTESTINE

Box plot of CZC24832 in ENKUR-low vs ENKUR-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration