ENG

Across TCGA cell cohorts, ENG RNA expression is significantly associated with the go_rna of many other GO terms, with 5,083 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ENG-associated GO terms across cancer lineages are Atrial cardiac muscle tissue morphogenesis, Regulation of fibroblast proliferation, and Negative regulation of cilium assembly. Each is linked with ENG in more than 16 cancer types. Because this analysis shows association rather than direction, both ENG-to-partner and partner-to-ENG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Atrial cardiac muscle tissue morphogenesis grouped by ENG-low versus ENG-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ENG→partner) and Y-score (partner→ENG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Atrial cardiac muscle tissue morphogenesis →	+1.580	+2.380	<.001	<.001	3	17
OVARY	Regulation of fibroblast proliferation →	+0.096	+1.617	<.001	.006	3	12
OESOPHAGUS	Negative regulation of cilium assembly →	+0.087	+2.136	.001	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Vesicle-mediated transport to the plasma membrane →	+0.101	+1.699	<.001	<.001	3	11
BONE	Vasculogenesis →	+0.155	+2.037	<.001	<.001	3	11
BONE	Epithelial to mesenchymal transition involved in endocardial cushion formation →	+0.210	+1.460	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,083 associations by consensus.

Atrial cardiac muscle tissue morphogenesis by ENG expression — URINARY_TRACT

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