ENDOU

Across TCGA cell cohorts, ENDOU mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ENDOU-associated genes across cancer lineages are OR52A5, OR52E2, and OR10W1. Each is linked with ENDOU in more than 1 cancer types. Because this analysis shows association rather than direction, both ENDOU-to-partner and partner-to-ENDOU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52A5 grouped by ENDOU-low versus ENDOU-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENDOU→partner) and Y-score (partner→ENDOU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR52A5 →	+0.012	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	OR52E2 →	+0.379	+4.887	<.001	.009	3	1
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
STOMACH	FOXB2 →	+0.013	+5.285	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

OR52A5 by ENDOU expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →