ENDOD1

Across TCGA patient cohorts, ENDOD1 mutation is significantly associated with the RNA expression of many other genes, with 784 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENDOD1-associated genes across cancer lineages are CYCSP49, YWHAQP1, and POLR3KP2. Each is linked with ENDOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ENDOD1-to-partner and partner-to-ENDOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CYCSP49 grouped by ENDOD1-low versus ENDOD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENDOD1→partner) and Y-score (partner→ENDOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	CYCSP49 →	+0.327	+7.142	<.001	<.001	3	2
COAD	YWHAQP1 →	+0.210	+5.435	<.001	.005	3	2
COAD	POLR3KP2 →	+0.431	+6.003	<.001	.002	3	2
CESC	MIR576 →	+0.502	+4.193	<.001	.009	3	2
CESC	RPL12P3 →	+0.214	+4.996	<.001	.002	3	2
KIRP	RAB9AP4 →	+0.071	+6.301	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 784 associations by consensus.

CYCSP49 by ENDOD1 expression — COAD

Explore this box plot interactively →