EN2

Across TCGA patient cohorts, EN2 protein abundance is significantly associated with the protein abundance of many other proteins, with 418 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EN2-associated proteins across cancer lineages are ABTB2, BUB3_S211, and CCT6A_S205. Each is linked with EN2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EN2-to-partner and partner-to-EN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EN2 versus ABTB2 in UCEC, with a Pearson correlation of 0.82.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EN2→partner) and Y-score (partner→EN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ABTB2 →	+0.681	+3.206	<.001	<.001	3	1
UCEC	BUB3_S211 →	-0.579	-3.241	<.001	<.001	3	1
UCEC	CCT6A_S205 →	+0.792	+3.404	<.001	<.001	3	1
UCEC	AFAP1L1_S98 →	-1.000	-3.116	<.001	.002	3	1
UCEC	CMTM3_S177 →	-1.693	-3.065	<.001	.001	3	1
UCEC	CMTM3_S179 →	-1.693	-3.065	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 418 associations by consensus.

EN2 vs ABTB2 — UCEC

Explore this scatter interactively →