EMX1

Across TCGA patient cohorts, EMX1 mutation is significantly associated with the RNA expression of many other genes, with 202 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMX1-associated genes across cancer lineages are RNU6-1292P, RN7SL316P, and RNA5SP419. Each is linked with EMX1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EMX1-to-partner and partner-to-EMX1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1292P grouped by EMX1-low versus EMX1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMX1→partner) and Y-score (partner→EMX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1292P →	+0.205	+4.469	<.001	.006	3	3
UCEC	RN7SL316P →	+0.240	+2.429	.002	.004	3	2
UCEC	RNA5SP419 →	+0.967	+2.591	<.001	.004	3	2
UCEC	RNA5SP422 →	+1.155	+2.671	<.001	.002	3	2
UCEC	RNA5SP416 →	+0.872	+2.738	<.001	.003	3	2
UCEC	RNA5SP421 →	+1.006	+2.603	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 202 associations by consensus.

RNU6-1292P by EMX1 expression — SKCM

Explore this box plot interactively →