EMSLR

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EMSLR RNA expression is significantly associated with the protein abundance of many other proteins, with 15,498 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EMSLR-associated proteins across cancer lineages are POLR1A, SUPT16H, and MCMBP. Each is linked with EMSLR in more than 7 cancer types. Because this analysis shows association rather than direction, both EMSLR-to-partner and partner-to-EMSLR results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMSLR versus POLR1A in LSCC, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EMSLR→partner) and Y-score (partner→EMSLR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCPOLR1A →+0.282+0.679<.001<.00138
LSCCSUPT16H →+0.415+0.769<.001<.00137
BRCAMCMBP →+0.324+0.948<.001<.00137
BRCARBM17 →+0.202+0.702<.001<.00136
LUADCDC20_T70 →+0.827+0.472.009.00236
LSCCTRMT5 →+0.265+0.477<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 15,498 associations by consensus.

EMSLR vs POLR1A — LSCC

Per-sample scatter of EMSLR vs POLR1A in LSCC (Pearson r = 0.52).

Explore this scatter interactively →

Exploration