EMP3

Across TCGA cell cohorts, EMP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,570 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EMP3-associated GO terms across cancer lineages are Regulation of collagen metabolic process, Regulation of plasminogen activation, and Peptidyl-lysine oxidation. Each is linked with EMP3 in more than 15 cancer types. Because this analysis shows association rather than direction, both EMP3-to-partner and partner-to-EMP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of collagen metabolic process grouped by EMP3-low versus EMP3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP3→partner) and Y-score (partner→EMP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of collagen metabolic process →	+0.184	+4.237	.001	<.001	3	16
BONE	Regulation of plasminogen activation →	+0.388	+1.262	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Peptidyl-lysine oxidation →	+1.403	+3.982	<.001	<.001	3	15
PANCREAS	Positive regulation of collagen biosynthetic process →	+0.199	+3.199	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	+0.254	+4.534	<.001	<.001	3	15
LUNG_NSCLC_LUSC	Positive regulation of supramolecular fiber organization →	+0.113	+3.847	.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,570 associations by consensus.

Regulation of collagen metabolic process by EMP3 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →