Across TCGA cell cohorts, EMP2 mutation is significantly associated with the RNA expression of many other genes, with 4 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible EMP2-associated genes across cancer lineages are SCN10A, TRIM64B, and SPO11. Each is linked with EMP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMP2-to-partner and partner-to-EMP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMP2→partner) and Y-score (partner→EMP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SCN10A →	+0.063	+5.029	<.001	.006	3	1
LUNG_SCLC	TRIM64B →	+0.034	+5.029	.003	.006	3	1
LUNG_SCLC	SPO11 →	+0.066	+5.029	<.001	.006	3	1
LARGE_INTESTINE	SLC15A5 →	+0.023	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Exploration

EMP2 survival (RNA) · tumor vs normal (RNA) · all EMP2 data types