Across TCGA patient cohorts, EMILIN3 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMILIN3-associated genes across cancer lineages are ATM, ERK2, and JNK_pT183_Y185. Each is linked with EMILIN3 in more than 2 cancer types. Because this analysis shows association rather than direction, both EMILIN3-to-partner and partner-to-EMILIN3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMILIN3→partner) and Y-score (partner→EMILIN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.465	-2.115	.018	.019	3	3
UCEC	ERK2 →	+0.205	+2.115	.014	.019	3	2
UCEC	JNK_pT183_Y185 →	-0.225	-2.321	.002	.034	3	2
UCEC	p70-S6K_pT389 →	-0.228	-3.321	.006	.009	3	2
SKCM	CD31 →	-0.173	-3.169	.012	.018	3	2
UCEC	4E-BP1 →	+0.453	+2.807	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

EMILIN3 survival (RNA) · tumor vs normal (RNA) · all EMILIN3 data types