EMILIN1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, EMILIN1 mutation is significantly associated with the RNA expression of many other genes, with 716 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EMILIN1-associated genes across cancer lineages are MYH8, FAM47B, and SLCO6A1. Each is linked with EMILIN1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EMILIN1-to-partner and partner-to-EMILIN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH8 grouped by EMILIN1-low versus EMILIN1-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMILIN1→partner) and Y-score (partner→EMILIN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTMYH8 →+0.015+3.781<.001.00932
BREASTFAM47B →+0.008+3.781<.001.00932
BREASTSLCO6A1 →+0.122+3.415<.001.00432
UPPER_AERODIGESTIVE_TRACTGYPB →+0.132+4.736<.001.00932
BLOOD_LeukemiaVWC2L →+0.010+4.339<.001.00232
LARGE_INTESTINEIL7 →+0.924+3.829<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 716 associations by consensus.

MYH8 by EMILIN1 expression — BREAST

Box plot of MYH8 in EMILIN1-low vs EMILIN1-high samples in BREAST.

Explore this box plot interactively →

Exploration