EMG1

Across TCGA patient cohorts, EMG1 mutation is significantly associated with the immune_cell of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMG1-associated genes across cancer lineages are Monocytes, NK cells, and pDC. Each is linked with EMG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMG1-to-partner and partner-to-EMG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Monocytes grouped by EMG1-low versus EMG1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMG1→partner) and Y-score (partner→EMG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Monocytes →	+0.012	+6.810	<.001	.017	3	1
STAD	NK cells →	+0.004	+5.597	.004	.040	3	1
UCEC	pDC →	+0.060	+2.180	.018	.036	3	1
UCEC	Macrophages M2 →	+0.014	+3.439	.011	.004	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

Monocytes by EMG1 expression — SKCM

Explore this box plot interactively →