EMG1

Across TCGA pan-cancer cohorts, EMG1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated EMG1 data layer compared with 3 for mutation status and 6 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher EMG1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EMG1 expression acts as an unfavorable survival marker, although some lineages such as SCLC and BRCA show a favorable association.

KIRC, UVM, and LIHC are the cancer types where EMG1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Tertile	III,IV	0.561	0.842	<.001	116	view →
UVM	OS	Median	All	0.473	1.000	.004	74	view →
LIHC	OS	Median	All	0.616	0.754	<.001	73	view →
MESO	OS	Median	All	0.430	0.657	<.001	68	view →
ACC	OS	Quartile	All	0.303	0.785	.002	33	view →
SARC	DFS	Median	All	0.420	0.600	<.001	29	view →
SCLC	OS	Quartile	II,III,IV	0.608	0.163	.006	28	view →
SKCM	DFS	Median	II,III,IV	0.595	0.802	.001	23	view →
KIRP	OS	Median	All	0.487	0.883	.002	19	view →
LUAD	DFS	Median	All	0.271	0.464	<.001	18	view →
BRCA	OS	Median	IV	0.822	0.335	.001	16	view →
DLBC	DFS	Quartile	II,III,IV	0.297	1.000	.022	13	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

EMG1–KIRC (DFS)

Open the KIRC breakdown →