EME1

Across TCGA patient cohorts, EME1 RNA expression is significantly associated with the protein abundance of many other proteins, with 24,933 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible EME1-associated proteins across cancer lineages are PTPN2_S304, SMC2, and SMC4. Each is linked with EME1 in more than 9 cancer types. Because this analysis shows association rather than direction, both EME1-to-partner and partner-to-EME1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EME1 versus PTPN2_S304 in BRCA, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EME1→partner) and Y-score (partner→EME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PTPN2_S304 →	+0.837	+0.854	.001	<.001	3	10
GBM	SMC2 →	+0.719	+0.734	<.001	<.001	3	10
GBM	SMC4 →	+0.712	+0.737	<.001	<.001	3	10
LSCC	HAT1 →	+0.535	+0.848	<.001	<.001	3	10
LUAD	KPNA2 →	+0.775	+0.875	<.001	<.001	3	10
HNSC	LIG1_S76 →	+0.940	+1.088	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,933 associations by consensus.

EME1 vs PTPN2_S304 — BRCA

Explore this scatter interactively →