EMCN

Across TCGA pan-cancer cohorts, EMCN mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated EMCN data layer compared with 24 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher EMCN mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated EMCN expression acts as an unfavorable survival marker, although some lineages such as HNSC and CCRCC show a favorable association.

HNSC, CCRCC, and UCEC are the cancer types where EMCN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.953	0.622	.001	42	view →
CCRCC	OS	Median	III,IV	0.836	0.565	.006	23	view →
UCEC	OS	Median	III,IV	0.414	1.000	.026	8	view →
LSCC	DFS	Quartile	All	0.873	1.000	.024	1	view →
LUAD	DFS	Quartile	II,III,IV	0.659	0.958	.045	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

EMCN–HNSC (OS)

Open the HNSC breakdown →