EMCN

Across TCGA patient cohorts, EMCN protein abundance is significantly associated with the RNA expression of many other genes, with 9,483 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EMCN-associated genes across cancer lineages are RAMP2, CAVIN2, and S1PR1. Each is linked with EMCN in more than 6 cancer types. Because this analysis shows association rather than direction, both EMCN-to-partner and partner-to-EMCN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMCN versus RAMP2 in COAD, with a Pearson correlation of 0.65.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMCN→partner) and Y-score (partner→EMCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RAMP2 →	+0.890	+0.929	.007	.002	3	7
CCRCC	CAVIN2 →	+1.410	+1.180	<.001	<.001	3	7
GBM	S1PR1 →	+0.970	+0.957	<.001	<.001	3	7
UCEC	ZBTB16 →	+1.697	+0.855	.006	.002	3	6
CCRCC	TAL1 →	+0.919	+1.153	<.001	<.001	3	6
OV	SELP →	+1.178	+0.797	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,483 associations by consensus.

EMCN vs RAMP2 — COAD

Explore this scatter interactively →