EMCN

Across TCGA cell cohorts, EMCN RNA expression is significantly associated with the go_rna of many other GO terms, with 1,140 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible EMCN-associated GO terms across cancer lineages are B cell chemotaxis, Positive regulation of ferroptosis, and RNA polymerase II transcription initiation surveillance. Each is linked with EMCN in more than 3 cancer types. Because this analysis shows association rather than direction, both EMCN-to-partner and partner-to-EMCN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell chemotaxis grouped by EMCN-low versus EMCN-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMCN→partner) and Y-score (partner→EMCN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	B cell chemotaxis →	-0.738	-0.472	.001	.008	3	4
BLOOD_Leukemia	Positive regulation of ferroptosis →	+0.082	+0.600	<.001	.003	3	3
BLOOD_Leukemia	RNA polymerase II transcription initiation surveillance →	+0.036	+0.432	.004	.008	3	3
BONE	Cellular response to salt →	+0.117	+0.688	.009	.006	3	3
BONE	Cellular response to sodium arsenite →	+0.136	+0.700	.005	.005	3	3
BONE	Regulation of cytoplasmic translational initiation →	+0.097	+1.036	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,140 associations by consensus.

B cell chemotaxis by EMCN expression — SOFT_TISSUE

Explore this box plot interactively →