EMC7

Across TCGA patient cohorts, EMC7 RNA expression is significantly associated with the mutation status of many other genes, with 12,060 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMC7-associated genes across cancer lineages are DNAH3, FAT3, and TP53. Each is linked with EMC7 in more than 4 cancer types. Because this analysis shows association rather than direction, both EMC7-to-partner and partner-to-EMC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNAH3 grouped by EMC7-low versus EMC7-high in COAD.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC7→partner) and Y-score (partner→EMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DNAH3 →	+2.441	+0.301	.001	<.001	3	5
STAD	FAT3 →	+1.609	+0.184	<.001	.006	3	5
SKCM	TP53 →	+1.812	+0.254	.002	.005	3	4
LUSC	RNF213 →	+2.105	+0.271	.003	.001	2	5
STAD	MUC5B →	+2.226	+0.251	<.001	.001	3	4
COAD	C10orf90 →	+2.947	+0.327	<.001	.007	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,060 associations by consensus.

DNAH3 by EMC7 expression — COAD

Explore this box plot interactively →