EMC7

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EMC7 protein abundance is significantly associated with the RNA expression of many other genes, with 12,308 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible EMC7-associated genes across cancer lineages are CEP55, RRM2, and CHRDL1. Each is linked with EMC7 in more than 3 cancer types. Because this analysis shows association rather than direction, both EMC7-to-partner and partner-to-EMC7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC7 versus CEP55 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC7→partner) and Y-score (partner→EMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCACEP55 →+1.031+0.252<.001.00434
OVRRM2 →+0.969+0.201<.001.00434
UCECCHRDL1 →-1.759-0.466<.001<.00134
HNSCIFT140 →-0.692-0.168<.001.00434
UCECPTGER3 →-1.432-0.322<.001.00234
CCRCCPLSCR4 →-0.735-0.267<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,308 associations by consensus.

EMC7 vs CEP55 — BRCA

Per-sample scatter of EMC7 vs CEP55 in BRCA (Pearson r = 0.31).

Explore this scatter interactively →

Exploration