EMC7

Across TCGA cell cohorts, EMC7 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,711 significant associations in total. BONE shows the largest number of these associations.

The most reproducible EMC7-associated GO terms across cancer lineages are Positive regulation of protein exit from endoplasmic reticulum, Endoplasmic reticulum organization, and Positive regulation of translational initiation in response to stress. Each is linked with EMC7 in more than 11 cancer types. Because this analysis shows association rather than direction, both EMC7-to-partner and partner-to-EMC7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein exit from endoplasmic reticulum grouped by EMC7-low versus EMC7-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC7→partner) and Y-score (partner→EMC7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of protein exit from endoplasmic reticulum →	+0.123	+0.794	<.001	<.001	3	12
BLOOD_Myeloma	Endoplasmic reticulum organization →	+0.087	+0.951	<.001	<.001	2	12
BONE	Positive regulation of translational initiation in response to stress →	+0.173	+0.810	<.001	<.001	3	11
BONE	Regulation of COPII vesicle coating →	+0.187	+1.094	<.001	<.001	3	10
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.071	+0.714	.001	<.001	3	10
SOFT_TISSUE	Regulation of protein exit from endoplasmic reticulum →	+0.132	+0.935	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,711 associations by consensus.

Positive regulation of protein exit from endoplasmic reticulum by EMC7 expression — STOMACH

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