EMC3-AS1

Across TCGA pan-cancer cohorts, EMC3-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated EMC3-AS1 data layer.

The strongest signal is observed in mesothelioma (MESO), where higher EMC3-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated EMC3-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and UCEC show a favorable association.

MESO, ACC, and KIRC are the cancer types where EMC3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
MESO	DFS	Median	All	0.245	0.479	<.001	127	view →
ACC	OS	Median	All	0.397	0.818	<.001	124	view →
KIRC	OS	Median	All	0.463	0.712	<.001	119	view →
KICH	DFS	Median	III,IV	0.246	0.942	<.001	109	view →
LIHC	DFS	Median	All	0.452	0.634	<.001	92	view →
UCS	DFS	Median	IV	0.952	0.367	.001	60	view →
LGG	OS	Tertile	All	0.710	0.875	<.001	42	view →
COAD	OS	Median	II,III,IV	0.694	0.872	.002	28	view →
SARC	DFS	Tertile	All	0.455	0.753	<.001	27	view →
STAD	DFS	Median	III,IV	0.489	0.669	.014	23	view →
UCEC	DFS	Quartile	IV	0.634	0.159	.010	22	view →
SKCM	DFS	Quartile	II,III,IV	0.777	0.520	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

EMC3-AS1–MESO (DFS)

Open the MESO breakdown →