EMC3-AS1

Across TCGA pan-cancer cohorts, EMC3-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of EMC3-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where EMC3-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types EMC3-AS1 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

COAD, KIRP, and LUAD are the cancer types where EMC3-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EMC3-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.098	<.001	11	view →
KIRP	All	II,III,IV	+0.999	<.001	11	view →
LUAD	Male	II,III,IV	+1.312	<.001	9	view →
BLCA	All	All	+1.061	<.001	9	view →
LIHC	Male	All	+0.656	<.001	9	view →
STAD	All	II,III,IV	+1.023	<.001	8	view →
READ	All	All	+0.897	<.001	7	view →
HNSC	Male	All	+0.347	.004	7	view →
UCEC	All	III,IV	+1.619	<.001	6	view →
LUSC	Male	II,III,IV	+0.880	<.001	6	view →
BRCA	All	II,III,IV	+0.388	<.001	6	view →
CHOL	Male	All	+1.563	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

EMC3-AS1–COAD

Open the COAD breakdown →