EMC2

Across TCGA patient cohorts, EMC2 protein abundance is significantly associated with the RNA expression of many other genes, with 13,962 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible EMC2-associated genes across cancer lineages are ZNF25, JAK1, and PSMD7. Each is linked with EMC2 in more than 4 cancer types. Because this analysis shows association rather than direction, both EMC2-to-partner and partner-to-EMC2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC2 versus ZNF25 in HNSC, with a Pearson correlation of -0.29.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC2→partner) and Y-score (partner→EMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZNF25 →	-0.588	-0.188	.001	.003	3	5
BRCA	JAK1 →	-0.572	-0.247	.001	<.001	3	5
PDAC	PSMD7 →	+0.316	+0.227	.001	.003	3	4
HNSC	MYOM1 →	-0.924	-0.131	<.001	.001	3	4
GBM	ENPP2 →	-1.671	-0.203	<.001	.001	3	4
BRCA	KIAA1109 →	-0.542	-0.231	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,962 associations by consensus.

EMC2 vs ZNF25 — HNSC

Explore this scatter interactively →