EMC2

Across TCGA cell cohorts, EMC2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,893 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible EMC2-associated GO terms across cancer lineages are Response to arsenite ion, Cellular response to arsenite ion, and Blastocyst growth. Each is linked with EMC2 in more than 8 cancer types. Because this analysis shows association rather than direction, both EMC2-to-partner and partner-to-EMC2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to arsenite ion grouped by EMC2-low versus EMC2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC2→partner) and Y-score (partner→EMC2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Response to arsenite ion →	+0.109	+0.825	.002	.006	3	9
LUNG_NSCLC_LUSC	Cellular response to arsenite ion →	+0.109	+0.825	.002	.006	3	9
CNS	Blastocyst growth →	+0.126	+0.677	<.001	<.001	3	9
OVARY	Ribosomal large subunit export from nucleus →	+0.085	+0.661	.003	.003	3	8
BLOOD_Lymphoma	Endosome organization →	+0.029	+0.771	<.001	<.001	3	8
SKIN	Somatic recombination of immunoglobulin gene segments →	+0.052	+0.520	.008	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,893 associations by consensus.

Response to arsenite ion by EMC2 expression — LUNG_NSCLC_LUSC

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