EMC10

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EMC10 protein abundance is significantly associated with the RNA expression of many other genes, with 7,165 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EMC10-associated genes across cancer lineages are EXTL1, FARS2, and P3H3. Each is linked with EMC10 in more than 3 cancer types. Because this analysis shows association rather than direction, both EMC10-to-partner and partner-to-EMC10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EMC10 versus EXTL1 in BRCA, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMC10→partner) and Y-score (partner→EMC10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAEXTL1 →-0.762-0.329.003.00634
UCECFARS2 →-0.488-0.297.002.00133
UCECP3H3 →-0.911-0.278<.001.00133
UCECCRY2 →-0.443-0.260.003.00233
UCECGSN →-0.936-0.245.001.00133
UCECVPS51 →-0.980-0.281<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,165 associations by consensus.

EMC10 vs EXTL1 — BRCA

Per-sample scatter of EMC10 vs EXTL1 in BRCA (Pearson r = -0.27).

Explore this scatter interactively →

Exploration