EMC1-AS1

Across TCGA pan-cancer cohorts, EMC1-AS1 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated EMC1-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher EMC1-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated EMC1-AS1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

KICH, HNSC, and SKCM are the cancer types where EMC1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	All	0.634	1.000	<.001	77	view →
HNSC	OS	Median	IV	0.693	0.511	<.001	48	view →
SKCM	DFS	Quartile	All	0.705	0.533	<.001	41	view →
LGG	DFS	Median	All	0.294	0.495	<.001	33	view →
OV	DFS	Tertile	III,IV	0.108	0.171	.013	26	view →
PAAD	DFS	Quartile	All	0.440	0.196	.008	25	view →
KIRP	DFS	Tertile	All	1.000	0.524	.001	22	view →
LIHC	OS	Tertile	All	0.335	0.689	<.001	22	view →
THYM	OS	Median	All	0.960	0.750	.008	21	view →
MESO	OS	Tertile	III,IV	0.433	0.232	.018	21	view →
UVM	DFS	Median	III,IV	0.912	0.446	.007	18	view →
ESCA	OS	Quartile	All	0.526	0.747	.023	17	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

EMC1-AS1–KICH (OS)

Open the KICH breakdown →