EMC1-AS1

Across TCGA pan-cancer cohorts, EMC1-AS1 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of EMC1-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where EMC1-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types EMC1-AS1 is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KICH, KIRC, and BLCA are the cancer types where EMC1-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EMC1-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−1.083	<.001	10	view →
KIRC	Female	All	+0.532	<.001	10	view →
BLCA	Male	III,IV	−0.781	.005	8	view →
THCA	Male	III,IV	−0.640	<.001	8	view →
LIHC	All	II,III,IV	+0.550	<.001	7	view →
UCEC	All	III,IV	−0.700	<.001	6	view →
KIRP	Male	All	−0.603	<.001	6	view →
BRCA	All	All	−0.533	<.001	6	view →
CHOL	All	All	+0.581	.021	2	view →
READ	All	III,IV	−0.445	.047	2	view →
ESCA	Female	All	−0.380	.031	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

EMC1-AS1–KICH

Open the KICH breakdown →