EMBP1

Across TCGA patient cohorts, EMBP1 mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible EMBP1-associated genes across cancer lineages are POM121L3P, RNU1-55P, and MIR489. Each is linked with EMBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both EMBP1-to-partner and partner-to-EMBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POM121L3P grouped by EMBP1-low versus EMBP1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EMBP1→partner) and Y-score (partner→EMBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	POM121L3P →	+0.014	+2.659	.007	.002	3	2
SKCM	RNU1-55P →	+0.089	+2.706	<.001	.004	3	2
SKCM	MIR489 →	+0.077	+4.816	<.001	.001	3	2
SKCM	SSXP9 →	+0.225	+2.787	<.001	.003	3	2
SKCM	ROBO2P1 →	+0.031	+4.228	<.001	.004	3	2
SKCM	KRTAP13-5P →	+0.032	+3.810	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

POM121L3P by EMBP1 expression — SKCM

Explore this box plot interactively →