ELP5

Across TCGA cell cohorts, ELP5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,615 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELP5-associated GO terms across cancer lineages are Telomere assembly, rRNA methylation, and Regulation of establishment of protein localization to chromosome. Each is linked with ELP5 in more than 12 cancer types. Because this analysis shows association rather than direction, both ELP5-to-partner and partner-to-ELP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere assembly grouped by ELP5-low versus ELP5-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP5→partner) and Y-score (partner→ELP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Telomere assembly →	+0.125	+0.923	<.001	.001	3	13
LARGE_INTESTINE	rRNA methylation →	+0.079	+1.034	<.001	<.001	3	11
SOFT_TISSUE	Regulation of establishment of protein localization to chromosome →	+0.131	+0.708	<.001	<.001	3	11
SOFT_TISSUE	Regulation of establishment of protein localization to telomere →	+0.131	+0.660	<.001	.001	3	11
BREAST	Regulation of telomere maintenance via telomerase →	+0.058	+1.185	.001	.001	3	10
URINARY_TRACT	Regulation of synaptic transmission, dopaminergic →	+0.194	+0.938	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,615 associations by consensus.

Telomere assembly by ELP5 expression — OVARY

Explore this box plot interactively →