ELP4

Across TCGA cell cohorts, ELP4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ELP4-associated genes across cancer lineages are PIP, TEX43, and CFHR2. Each is linked with ELP4 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELP4-to-partner and partner-to-ELP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PIP grouped by ELP4-low versus ELP4-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELP4→partner) and Y-score (partner→ELP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PIP →	+0.082	+4.705	<.001	.003	3	1
BLOOD_Leukemia	TEX43 →	+0.105	+4.969	<.001	.003	3	1
LARGE_INTESTINE	CFHR2 →	+0.038	+4.022	<.001	.006	3	1
BLOOD_Lymphoma	ODF4 →	+0.117	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR6X1 →	+0.022	+5.209	<.001	.005	3	1
BLOOD_Leukemia	SMIM32 →	+0.023	+4.169	.004	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

PIP by ELP4 expression — BLOOD_Leukemia

Explore this box plot interactively →