ELOVL6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELOVL6 mutation is significantly associated with the RNA expression of many other genes, with 4,580 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL6-associated genes across cancer lineages are MIR592, MIR4497, and RN7SL690P. Each is linked with ELOVL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL6-to-partner and partner-to-ELOVL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR592 grouped by ELOVL6-low versus ELOVL6-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL6→partner) and Y-score (partner→ELOVL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAMIR592 →+0.418+7.640<.001.00932
UCECMIR4497 →+0.226+2.095<.001.00732
SKCMRN7SL690P →+0.193+5.771<.001.00332
SKCMMIR4422 →+0.589+5.436<.001.00532
SKCMLINC02644 →+0.111+6.199<.001.00132
PRADDRD5P2 →+0.021+5.721<.001.00331
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,580 associations by consensus.

MIR592 by ELOVL6 expression — BLCA

Box plot of MIR592 in ELOVL6-low vs ELOVL6-high samples in BLCA.

Explore this box plot interactively →

Exploration