ELOVL6

Across TCGA patient cohorts, ELOVL6 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOVL6-associated genes across cancer lineages are eEF2, EGFR_pY1068, and eIF4E. Each is linked with ELOVL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOVL6-to-partner and partner-to-ELOVL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, eEF2 grouped by ELOVL6-low versus ELOVL6-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOVL6→partner) and Y-score (partner→ELOVL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.318	+2.459	.013	.018	3	1
UCEC	EGFR_pY1068 →	-0.290	-3.584	.001	.002	3	1
UCEC	eIF4E →	+0.191	+3.472	.011	.002	3	1
UCEC	eIF4G →	+0.272	+3.584	.015	.002	3	1
UCEC	ERK2 →	+0.226	+1.925	.001	.005	3	1
UCEC	Gab2 →	+0.278	+3.169	.030	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

eEF2 by ELOVL6 expression — UCEC

Explore this box plot interactively →