ELOC

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELOC RNA expression is significantly associated with the protein abundance of many other proteins, with 11,009 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ELOC-associated proteins across cancer lineages are YTHDF3, OTUD6B, and POP1. Each is linked with ELOC in more than 7 cancer types. Because this analysis shows association rather than direction, both ELOC-to-partner and partner-to-ELOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELOC versus YTHDF3 in OV, with a Pearson correlation of 0.58.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOC→partner) and Y-score (partner→ELOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVYTHDF3 →+0.282+0.502<.001<.00138
OVOTUD6B →+0.437+0.533<.001.00537
LUADPOP1 →+0.270+0.559<.001<.00137
OVVCPIP1 →+0.322+0.707<.001<.00137
BRCAAGO1 →-0.231-0.406.005.00537
BRCASTK3 →+0.314+0.367<.001.00236
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,009 associations by consensus.

ELOC vs YTHDF3 — OV

Per-sample scatter of ELOC vs YTHDF3 in OV (Pearson r = 0.58).

Explore this scatter interactively →

Exploration