ELOC

Across TCGA patient cohorts, ELOC protein abundance is significantly associated with the RNA expression of many other genes, with 10,216 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ELOC-associated genes across cancer lineages are NPEPPS, POLR3K, and RCSD1. Each is linked with ELOC in more than 4 cancer types. Because this analysis shows association rather than direction, both ELOC-to-partner and partner-to-ELOC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELOC versus NPEPPS in CCRCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOC→partner) and Y-score (partner→ELOC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	NPEPPS →	+0.473	+0.164	<.001	<.001	3	5
BRCA	POLR3K →	+0.696	+0.249	<.001	.003	3	5
HNSC	RCSD1 →	-0.592	-0.158	.008	.005	3	5
UCEC	DNAJA3 →	+0.598	+0.197	<.001	<.001	2	5
LUAD	LRRCC1 →	+0.536	+0.116	<.001	.004	3	4
UCEC	SNRNP25 →	+1.054	+0.161	.001	.006	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,216 associations by consensus.

ELOC vs NPEPPS — CCRCC

Explore this scatter interactively →