ELOB

Across TCGA patient cohorts, ELOB protein abundance is significantly associated with the RNA expression of many other genes, with 17,379 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible ELOB-associated genes across cancer lineages are COPS6, CXCL2, and DNAJA3. Each is linked with ELOB in more than 4 cancer types. Because this analysis shows association rather than direction, both ELOB-to-partner and partner-to-ELOB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELOB versus COPS6 in UCEC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOB→partner) and Y-score (partner→ELOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COPS6 →	+0.817	+0.212	<.001	<.001	3	5
LSCC	CXCL2 →	-1.324	-0.136	<.001	<.001	3	4
UCEC	DNAJA3 →	+0.613	+0.206	<.001	<.001	3	4
UCEC	PYCR3 →	+0.798	+0.181	<.001	<.001	3	4
PDAC	P2RX1 →	-0.724	-0.119	<.001	<.001	3	4
LUAD	NPEPPS →	+0.528	+0.164	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,379 associations by consensus.

ELOB vs COPS6 — UCEC

Explore this scatter interactively →