ELOB

Across TCGA pan-cancer cohorts, ELOB RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ELOB’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ELOB RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELOB is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KIRP, COAD, and LIHC are the cancer types where ELOB tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELOB RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	III,IV	+0.842	<.001	11	view →
COAD	Female	All	+1.234	<.001	9	view →
LIHC	Female	II,III,IV	+1.031	<.001	8	view →
KIRC	Female	All	+0.486	<.001	8	view →
HNSC	Male	All	+0.390	.001	8	view →
STAD	All	All	+0.414	.002	7	view →
BRCA	All	III,IV	+0.868	<.001	6	view →
KICH	All	All	−0.557	<.001	5	view →
LUAD	Female	II,III,IV	+0.474	.004	5	view →
LUSC	All	All	+0.370	<.001	4	view →
CHOL	All	All	+1.339	<.001	3	view →
THCA	All	All	+0.316	.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ELOB–KIRP

Open the KIRP breakdown →