ELOB

Across TCGA patient cohorts, ELOB mutation is significantly associated with the RNA expression of many other genes, with 97 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELOB-associated genes across cancer lineages are YTHDF3-AS1, DDX55P1, and SNRPGP17. Each is linked with ELOB in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOB-to-partner and partner-to-ELOB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, YTHDF3-AS1 grouped by ELOB-low versus ELOB-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOB→partner) and Y-score (partner→ELOB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	YTHDF3-AS1 →	+0.869	+3.223	<.001	.009	3	1
UCEC	DDX55P1 →	+0.191	+3.712	<.001	.003	3	1
UCEC	SNRPGP17 →	+0.342	+2.463	.001	.008	3	1
UCEC	HMGB1P50 →	+0.230	+2.998	<.001	.001	3	1
UCEC	RPS29P32 →	+0.763	+3.014	<.001	.004	3	1
UCEC	RN7SL478P →	+0.366	+2.939	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 97 associations by consensus.

YTHDF3-AS1 by ELOB expression — UCEC

Explore this box plot interactively →