Across TCGA pan-cancer cohorts, ELOAP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ELOAP1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ELOAP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELOAP1 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
HNSC and PAAD are the cancer types where ELOAP1 tumor–normal differential expression is most reproducible.