ELOA

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELOA protein abundance is significantly associated with the RNA expression of many other genes, with 12,107 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ELOA-associated genes across cancer lineages are PARK7, MTFR1L, and DFFA. Each is linked with ELOA in more than 4 cancer types. Because this analysis shows association rather than direction, both ELOA-to-partner and partner-to-ELOA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELOA versus PARK7 in OV, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOA→partner) and Y-score (partner→ELOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVPARK7 →+0.464+0.209<.001<.00135
OVMTFR1L →+0.472+0.212.001.00635
OVDFFA →+0.743+0.250<.001<.00135
LUADPDIK1L →+0.606+0.333<.001<.00135
LSCCMRPL20-AS1 →+0.518+0.285<.001<.00135
OVMRTO4 →+0.388+0.254<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,107 associations by consensus.

ELOA vs PARK7 — OV

Per-sample scatter of ELOA vs PARK7 in OV (Pearson r = 0.41).

Explore this scatter interactively →

Exploration