ELOA

Across TCGA cell cohorts, ELOA mutation is significantly associated with the RNA expression of many other genes, with 1,637 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELOA-associated genes across cancer lineages are OOSP4A, TFDP3, and LCE2A. Each is linked with ELOA in more than 1 cancer types. Because this analysis shows association rather than direction, both ELOA-to-partner and partner-to-ELOA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OOSP4A grouped by ELOA-low versus ELOA-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELOA→partner) and Y-score (partner→ELOA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	OOSP4A →	+0.053	+4.930	<.001	.008	3	2
PANCREAS	TFDP3 →	+0.013	+5.000	<.001	.006	3	1
PANCREAS	LCE2A →	+0.033	+5.614	<.001	.002	3	1
PANCREAS	OR2J1 →	+0.006	+5.614	<.001	.002	3	1
PANCREAS	XKR4 →	+0.059	+5.000	<.001	.006	3	1
PANCREAS	KRTAP1-3 →	+0.042	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,637 associations by consensus.

OOSP4A by ELOA expression — SOFT_TISSUE

Explore this box plot interactively →