ELN-AS1

Across TCGA pan-cancer cohorts, ELN-AS1 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated ELN-AS1 data layer.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ELN-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated ELN-AS1 expression acts as an unfavorable survival marker, although some lineages such as BRCA and UCEC show a favorable association.

BRCA, GBM, and UCEC are the cancer types where ELN-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Tertile	All	0.956	0.902	<.001	43	view →
GBM	DFS	Median	All	0.187	0.387	.002	33	view →
UCEC	OS	Quartile	All	0.966	0.892	.018	32	view →
UCS	DFS	Median	IV	0.885	0.440	.015	30	view →
KIRC	DFS	Quartile	All	0.811	0.938	.008	28	view →
LGG	OS	Median	All	0.853	0.934	<.001	27	view →
LUAD	OS	Median	All	0.855	0.767	.001	22	view →
PAAD	DFS	Median	All	0.358	0.199	.017	21	view →
DLBC	DFS	Median	IV	0.128	1.000	.017	16	view →
LUSC	OS	Median	II,III,IV	0.524	0.694	.008	16	view →
SARC	OS	Quartile	All	0.571	0.332	.004	15	view →
READ	DFS	Quartile	II,III,IV	0.928	0.538	.018	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

ELN-AS1–BRCA (OS)

Open the BRCA breakdown →