ELMOD3

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ELMOD3 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELMOD3-associated genes across cancer lineages are PDILT, ZNF454, and FAM205C. Each is linked with ELMOD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMOD3-to-partner and partner-to-ELMOD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PDILT grouped by ELMOD3-low versus ELMOD3-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMOD3→partner) and Y-score (partner→ELMOD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEPDILT →+0.006+4.022<.001.00631
LARGE_INTESTINEZNF454 →+0.319+3.658<.001.00531
LARGE_INTESTINEFAM205C →+0.010+4.022<.001.00631
OVARYOR8K3 →+0.035+5.196<.001.00531
LARGE_INTESTINEWDR87 →+0.017+3.453.003.00921
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PDILT by ELMOD3 expression — LARGE_INTESTINE

Box plot of PDILT in ELMOD3-low vs ELMOD3-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration