ELMOD1

Across TCGA cell cohorts, ELMOD1 mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ELMOD1-associated genes across cancer lineages are TP53TG3E, MOGAT1, and C10orf53. Each is linked with ELMOD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMOD1-to-partner and partner-to-ELMOD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53TG3E grouped by ELMOD1-low versus ELMOD1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMOD1→partner) and Y-score (partner→ELMOD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TP53TG3E →	+0.036	+4.289	<.001	<.001	3	2
LARGE_INTESTINE	MOGAT1 →	+0.104	+3.878	<.001	.003	3	1
LARGE_INTESTINE	C10orf53 →	+0.012	+3.632	<.001	.003	3	1
LUNG_NSCLC_LUAD	GTSF1L →	+0.047	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	HES3 →	+0.090	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	BEND2 →	+0.010	+4.544	.004	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

TP53TG3E by ELMOD1 expression — BLOOD_Leukemia

Explore this box plot interactively →