ELMO3

Across TCGA patient cohorts, ELMO3 mutation is significantly associated with the RNA expression of many other genes, with 1,167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ELMO3-associated genes across cancer lineages are OR8K4P, TSPY5P, and RPL31P54. Each is linked with ELMO3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELMO3-to-partner and partner-to-ELMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8K4P grouped by ELMO3-low versus ELMO3-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO3→partner) and Y-score (partner→ELMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	OR8K4P →	+0.059	+7.930	<.001	.008	3	2
HNSC	TSPY5P →	+0.052	+4.636	.007	.006	3	2
HNSC	RPL31P54 →	+0.107	+4.888	.001	<.001	3	2
UCEC	COX15 →	+0.382	+2.230	.004	.006	3	2
UCEC	ALDOA →	+0.553	+2.247	<.001	.002	3	2
UCEC	CHAF1B →	+0.584	+2.238	.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,167 associations by consensus.

OR8K4P by ELMO3 expression — LUAD

Explore this box plot interactively →