ELMO3

Across TCGA cell cohorts, ELMO3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,469 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ELMO3-associated GO terms across cancer lineages are Regulation of clathrin coat assembly, Response to indole-3-methanol, and Establishment of epithelial cell apical/basal polarity. Each is linked with ELMO3 in more than 13 cancer types. Because this analysis shows association rather than direction, both ELMO3-to-partner and partner-to-ELMO3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of clathrin coat assembly grouped by ELMO3-low versus ELMO3-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ELMO3→partner) and Y-score (partner→ELMO3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Regulation of clathrin coat assembly →	+0.212	+1.533	.002	.003	2	14
OESOPHAGUS	Response to indole-3-methanol →	+0.230	+2.131	<.001	.001	3	13
LUNG_NSCLC_LUSC	Establishment of epithelial cell apical/basal polarity →	-0.200	-1.708	<.001	<.001	3	13
LUNG_NSCLC_LUSC	Cellular response to indole-3-methanol →	+0.256	+2.128	<.001	<.001	3	12
LUNG_SCLC	Negative regulation of Arp2/3 complex-mediated actin nucleation →	+0.244	+1.092	<.001	.001	3	12
STOMACH	Regulation of viral budding via host ESCRT complex →	+0.143	+2.340	.002	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,469 associations by consensus.

Regulation of clathrin coat assembly by ELMO3 expression — URINARY_TRACT

Explore this box plot interactively →