ELL2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ELL2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,872 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ELL2-associated genes across cancer lineages are MEN1, CPSF7, and IGHV3OR16-7. Each is linked with ELL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELL2-to-partner and partner-to-ELL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELL2 versus MEN1 in HNSC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL2→partner) and Y-score (partner→ELL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCMEN1 →-0.500-0.404.001.00332
HNSCCPSF7 →-0.478-0.373.002.00432
LSCCIGHV3OR16-7 →+0.523+0.438.002<.00132
LSCCFBXO21 →-0.509-0.465<.001.00132
LSCCTHOC2 →-0.443-0.429.001.00132
UCECCCDC171 →-0.774-0.382.005.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,872 associations by consensus.

ELL2 vs MEN1 — HNSC

Per-sample scatter of ELL2 vs MEN1 in HNSC (Pearson r = -0.30).

Explore this scatter interactively →

Exploration