ELL2

Across TCGA cell cohorts, ELL2 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ELL2-associated genes across cancer lineages are PRSS45P, TMCO5A, and FSHB. Each is linked with ELL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ELL2-to-partner and partner-to-ELL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRSS45P grouped by ELL2-low versus ELL2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL2→partner) and Y-score (partner→ELL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	PRSS45P →	+0.124	+3.643	.003	.001	3	2
LARGE_INTESTINE	TMCO5A →	+0.019	+4.415	<.001	.007	3	1
BLOOD_Lymphoma	FSHB →	+0.007	+3.925	<.001	.006	3	1
BLOOD_Lymphoma	ALX3 →	+0.256	+3.556	<.001	.005	3	1
BLOOD_Lymphoma	LMX1A →	+0.023	+3.544	<.001	.001	3	1
BLOOD_Lymphoma	C2orf73 →	+0.036	+2.874	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

PRSS45P by ELL2 expression — BLOOD_Lymphoma

Explore this box plot interactively →