ELL

Across TCGA patient cohorts, ELL protein abundance is significantly associated with the RNA expression of many other genes, with 9,163 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ELL-associated genes across cancer lineages are CDKN3, NALCN, and CCNE1. Each is linked with ELL in more than 4 cancer types. Because this analysis shows association rather than direction, both ELL-to-partner and partner-to-ELL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ELL versus CDKN3 in UCEC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ELL→partner) and Y-score (partner→ELL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDKN3 →	+1.087	+0.273	<.001	<.001	3	5
GBM	NALCN →	-0.889	-0.248	.002	<.001	3	4
BRCA	CCNE1 →	+1.472	+0.404	<.001	<.001	3	4
LUAD	NEIL3 →	+0.854	+0.175	<.001	.004	3	4
LUAD	TTK →	+1.074	+0.250	<.001	<.001	3	4
UCEC	AUNIP →	+0.954	+0.328	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,163 associations by consensus.

ELL vs CDKN3 — UCEC

Explore this scatter interactively →