ELL

Across TCGA pan-cancer cohorts, ELL RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of ELL’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where ELL RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ELL is over-expressed in tumor, although a few such as KICH and KIRP show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where ELL tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ELL RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Female	III,IV	+0.827	<.001	12	view →
COAD	Female	All	+0.283	<.001	7	view →
LIHC	All	II,III,IV	+0.535	.001	6	view →
KICH	All	All	−0.624	<.001	5	view →
STAD	All	II,III,IV	+0.610	.002	4	view →
CHOL	Male	All	+1.180	<.001	2	view →
KIRP	All	All	−0.386	.005	2	view →
ESCA	All	All	+0.735	.005	1	view →
THCA	All	All	−0.145	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

ELL–HNSC

Open the HNSC breakdown →